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X-WR-CALNAME:Michigan Institute for Computational Discovery and Engineering
X-ORIGINAL-URL:https://micde.umich.edu
X-WR-CALDESC:Events for Michigan Institute for Computational Discovery and Engineering
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DTSTART:20150101T000000
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DTSTART;TZID=UTC:20160505T153000
DTEND;TZID=UTC:20160505T170000
DTSTAMP:20260614T160731
CREATED:20230905T171441Z
LAST-MODIFIED:20230905T171441Z
UID:10000022-1462462200-1462467600@micde.umich.edu
SUMMARY:Biostatistics Seminar: Kenneth Lange\, Professor of Biomathematics\, Human Genetics and Statistics\, UCLA: "Next Generation Statistical Genetics"
DESCRIPTION:This talk will discuss how modern data mining techniques can be imported into statistical genetics. Most relevant models now invoke high-dimensional optimization. Penalization and set projection give sparsity. Separation of variables gives parallelization. Time permitting\, these ideas will be illustrated by several examples: estimation of ethnic ancestry\, genotype imputation via matrix completion\, conversion of imputed genotypes into haplotypes\, matrix completion discriminant analysis\, estimation in the linear mixed model\, iterative hard thresholding in GWAS\, and sparse principal components analysis.
URL:https://micde.umich.edu/event/biostatistics-seminar-kenneth-lange-professor-of-biomathematics-human-genetics-and-statistics-ucla-next-generation-statistical-genetics/
LOCATION:1690 SPH I\, 1415 Washington Heights\, Ann Arbor\, MI\, United States
GEO:42.2807993;-83.7303417
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