With this solicitation, the Division of Chemistry is piloting the removal of deadlines for the submission of proposals to the CLP, CSDM-A and CTMC Programs. The no-deadline pilot seeks to assess the benefits and challenges of removing deadlines in proposal submission for the chemistry research community: the removal of deadlines on proposal submission is intended to allow principal investigators (PIs) more flexibility and better facilitate interdisciplinary research. It may, however, have unanticipated consequences for PIs, reviewers, and institutions. This solicitation applies only to the Chemistry of Life Processes (CLP), Chemical Structure, Dynamics, and Mechanisms-A (CSDM-A) and Chemical Theory, Models and Computational Methods (CTMC) programs. Other than the following exceptions, all proposals submitted to the CLP, CSDM-A, and CTMC programs must be submitted through this solicitation, otherwise they will be returned without review.