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Bio: Smita Krishnaswamy is an Associate Professor in the departments of Computer Science (SEAS) and Genetics (YSM). She is part of the programs in Applied Mathematics, Computational Biology & Bioinformatics and Interdisciplinary Neuroscience. She is also affiliated with the Yale Institute for the foundations of data science, Wu-Tsai Institute, Yale Cancer Center. Her lab works on fundamental deep learning and machine learning developments for representing and learning from big data. Her techniques incorporate mathematical priors from graph spectral theory, manifold learning, signal processing, and topology into machine learning and deep learning frameworks, in order to denoise and model the underlying systems faithfully for predictive insight. Currently her methods are being widely used for data denoising, visualization, generative modeling, dynamics. modeling, comparative analysis and domain transfer in datasets arising from stem cell biology, cancer, immunology and structural biology (among others).

Prior to joining Yale, she completed her postdoctoral training at Columbia University in the systems biology department where she focused on learning computational models of cellular signaling from single-cell mass cytometry data. She obtained her Ph.D. from EECS department at University of Michigan where her research focused on algorithms for automated synthesis and probabilistic verification of nanoscale logic circuits. Following her time in Michigan, she spent 2 years at IBM’s TJ Watson Research Center as a researcher in the systems division where she worked on automated bug finding and error correction in logic. Her work over the years has won several awards including the NSF CAREER Award, Sloan Faculty Fellowship, and Blavatnik fund for Innovation.

Dynamics Models of Cellular and Neuronal Interactions